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Luxe Prestige Chronicle

singulair withdrawal side effects

Author

Sarah Martinez

Updated on June 30, 2026

As far as long-term Singulair side effects, the side effects you might have from Singulair don’t change much even with longer treatment. Stopping Singulair suddenly typically doesn’t cause withdrawal symptoms that can make your asthma worse. But to be on the safe side, talk to your doctor before stopping.

Can I just stop taking montelukast?

Do not stop taking these medicines and do not reduce the dose, even if your asthma seems better, unless you or your child are told to do so by your doctor. Talk to your doctor or get medical care right away if: Your or your child’s symptoms do not improve after using this medicine or if they become worse.

How long does Singulair withdrawal symptoms last?

Montelukast (last week) and PSSD (the week before) make it clear that withdrawal syndromes can last for months, years and maybe even longer. Based on opioids and alcohol lasting 2-3 weeks, industry have sold doctors a story that withdrawal lasts 2-3 weeks – is transient.

Do you have to taper off montelukast?

You can taper by taking the medication every alternate day or by taking fexofenadine 60 mg and montelukast 4 or 5 mg which are available separately. Get your allergy tests done. Rule out dust mite allergy as your symptoms are worse in the first half of the day. Try to check why your symptoms are worse at certain times.

Can montelukast cause anxiety?

Those taking montelukast who exhibit mood changing behaviors should immediately report symptoms to a healthcare provider. These can include bad or vivid dreams, depression, disorientation or confusion, feeling anxious, hallucinations, irritability, restlessness, stuttering, and uncontrolled muscle movements.

Are Singulair side effects permanent?

According to an Asthma Australia fact sheet on Singulair, the side effects of the drug “are reversible once the medication is ceased”.

Why you should not take Singulair?

May cause psychiatric-type effects including agitation, aggressive behavior, anxiety, depression, abnormal dreams, and hallucinations. These have been reported in people of all ages taking Singulair. May cause dizziness or drowsiness and affect a person’s ability to drive and operate machinery.

Can Singulair 10 mg be cut in half?

Things you must not do

If you have been prescribed the 5 mg tablets, do not take half a 10 mg tablet in its place. The different strength tablets may not have the same effect, as they are absorbed slightly differently in the body.

Can Singulair cause you to gain weight?

Does Singulair (montelukast) cause weight gain? Weight gain is not a common side effect of Singulair (montelukast).

What does montelukast do to the brain?

Montelukast has been described to be neuroprotective, for example, in the aging brain and after focal cerebral ischemia7,8. In the aging brain, increased activation of microglia is accompanied with decreased hippocampal neurogenesis and cognitive decline7.

Can you take montelukast every other day?

Most people take montelukast once a day in the evening to prevent asthma or allergy symptoms. However, if exercise makes your asthma worse, your doctor might tell you to take montelukast 2 hours before you exercise. Never take more than 1 dose a day.

What can you take instead of Singulair?

Alternatives to Singulair for allergies

Singulair can be taken with many other over-the-counter or prescription drugs that treat allergies, including antihistamines like Claritin, Allegra, or Zyrtec, and intranasal steroid sprays such as Flonase or Nasacort.